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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZDHHC2 All Species: 19.39
Human Site: T255 Identified Species: 38.79
UniProt: Q9UIJ5 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UIJ5 NP_057437.1 367 42022 T255 S P V F R H G T D K N G F S L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001098564 322 36847 N213 F R H G T D K N G F S L G F S
Dog Lupus familis XP_532825 322 36792 N213 F R H G T D K N G F S L G F S
Cat Felis silvestris
Mouse Mus musculus P59267 366 41963 T254 N P V F R H G T D K N G F S L
Rat Rattus norvegicus Q9JKR5 366 42067 T254 N P V F R H G T D K N G F S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508925 327 37361 N218 F R H G T D K N G F S L G F S
Chicken Gallus gallus XP_420689 376 42780 T265 A P I F H H R T D K N G F S L
Frog Xenopus laevis Q5FWL7 338 39422 F229 M F F I S L M F L F G Y H C W
Zebra Danio Brachydanio rerio NP_001013510 361 41903 T252 A P A F Q H G T D K N G F S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q8I0G4 403 46434 Y283 A P M I D G K Y A K D A F N H
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYP5 307 34670 F198 M P H F I A F F S D E E I P G
Baker's Yeast Sacchar. cerevisiae P42836 336 39165 R227 T I E V H G M R R Y R R D L E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 86 85.5 N.A. 95 95.3 N.A. 77.3 82.4 50.6 74.3 N.A. N.A. N.A. 32.7 N.A.
Protein Similarity: 100 N.A. 86.6 86.3 N.A. 96.7 97.5 N.A. 80.9 89.3 67.8 84.4 N.A. N.A. N.A. 50.6 N.A.
P-Site Identity: 100 N.A. 0 0 N.A. 93.3 93.3 N.A. 0 73.3 0 80 N.A. N.A. N.A. 20 N.A.
P-Site Similarity: 100 N.A. 6.6 6.6 N.A. 100 100 N.A. 6.6 86.6 0 93.3 N.A. N.A. N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.2 24.2 N.A.
Protein Similarity: N.A. N.A. N.A. 47.1 41.4 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 9 0 0 9 0 0 9 0 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 0 0 0 0 9 25 0 0 42 9 9 0 9 0 0 % D
% Glu: 0 0 9 0 0 0 0 0 0 0 9 9 0 0 9 % E
% Phe: 25 9 9 50 0 0 9 17 0 34 0 0 50 25 0 % F
% Gly: 0 0 0 25 0 17 34 0 25 0 9 42 25 0 9 % G
% His: 0 0 34 0 17 42 0 0 0 0 0 0 9 0 9 % H
% Ile: 0 9 9 17 9 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 0 0 0 0 0 0 34 0 0 50 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 9 0 0 9 0 0 25 0 9 42 % L
% Met: 17 0 9 0 0 0 17 0 0 0 0 0 0 0 0 % M
% Asn: 17 0 0 0 0 0 0 25 0 0 42 0 0 9 0 % N
% Pro: 0 59 0 0 0 0 0 0 0 0 0 0 0 9 0 % P
% Gln: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 25 0 0 25 0 9 9 9 0 9 9 0 0 0 % R
% Ser: 9 0 0 0 9 0 0 0 9 0 25 0 0 42 25 % S
% Thr: 9 0 0 0 25 0 0 42 0 0 0 0 0 0 0 % T
% Val: 0 0 25 9 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 0 0 0 0 9 0 9 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _